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ORIGINAL ARTICLE
Year : 2013  |  Volume : 1  |  Issue : 3  |  Page : 171-173

Shift and drift in species of Candida in bloodstream infections of neonates


Department of Microbiology, Sri Aurobindo Institute of Medical Sciences Medical College, and PG Institute, Indore, Madhya Pradesh, India

Correspondence Address:
Gunjan Shrivastava
Department of Microbiology, Sri Aurobindo Institute of Medical Sciences Medical College and Post Graduate Institute, Indore, Madhya Pradesh - 453 555
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2347-9019.129159

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Context: Candidemia is a major cause of nosocomial morbidity and mortality in neonates. Although Candida albicans remains the most common fungal isolate from blood, longitudinal studies have detected a trend toward an increased prevalence of other Candida species. Aims: To study the changing pattern of candida species and their importance in bloodstream infection in neonates. Settings and Design: This is the 3-year respective study. Subjects and Methods: The neonates born or admitted during Jan 2010-Dec 2012 were included in the study. A total of 69 neonates with Candidemia as evidenced by positive blood cultures were considered. Peripheral blood samples were collected for culture, isolation and identification of Candida species by bacT/alert automated system, germ tube test and Vitek 2 cards for yeast identification. All the isolates were checked for purity and speciated by Chromagar. Statistical Analysis Used: No. Results: A total of 7.48% neonates had Candidemia. Non-albicans Candida was found in 85.5% of neonates while Candida albicans was found in only 14.5% neonates. Candida tropicalis (42%) was the predominant non-albicans Candida species isolated in our setting followed by Candida krusei (38%). Conclusion: There are multiple risk factors that are responsible for emergence of neonatal Candidemia in recent years. In conclusion, non-albicans Candida species are assuming an increasing role in nosocomial infections in neonates and finding of this study highlights the increased isolation of Candida tropicalis in our setting. The study emphasizes the identification of candida species to reduce morbidity and mortalities in the neonates.


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